University of Southern California

Georgia Lab

USC Stem Cell

Selected Publications

2013

  • Georgia S, Kanji M, Bhushan A. DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis. Genes Dev. 2013 Feb 15;27(4):372­–7. doi: 10.1101/gad.207001.112. PMID: 23431054. (Cover article) [PubMed] [PDF]

2011

  • Dhawan S, Georgia S, Tschen SI, Fan G, Bhushan A. Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx. Dev Cell. 2011 Apr 19;20(4):419–29. doi: 10.1016/j.devcel.2011.03.012. PMID: 21497756. [PubMed] [PDF]

2010

  • Georgia S, Hinault C, Kawamori D, Hu J, Meyer J, Kanji M, Bhushan A, Kulkarni RN. Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents. Diabetes. 2010 Apr;59(4):987–96. doi: 10.2337/db09-0838. PMID: 20103709. [PubMed] [PDF]

2007

  • Dhawan S, Georgia S, Bhushan A. Formation and regeneration of the endocrine pancreas. Curr Opin Cell Biol. 2007. Curr Opin Cell Biol. 2007 Dec;19(6):634–45. Review. PMID: 18061427. [PubMed] [PDF]
  • Zhong L, Georgia S, Tschen SI, Nakayama K, Nakayama K, Bhushan A. Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells. J Clin Invest. 2007 Oct;117(10):2869–76. PMID: 17823659. [PubMed] [PDF]

2006

  • Georgia S, Bhushan A. p27 Regulates the transition of beta-cells from quiescence to proliferation. Diabetes. 2006 Nov;55(11):2950–6. PMID: 17065330. [PubMed] [PDF]
  • Georgia S, Soliz R, Li M, Zhang P, Bhushan A. p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors. Dev Biol. 2006 Oct 1;298(1):22–31. PMID: 16899237. [PubMed] [PDF]

2004

  • Georgia S, Bhushan A. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. J Clin Invest. 2004 Oct;114(7):963–8. PMID: 15467835. (Cover article) [PubMed] [PDF]